IGVFDS3910MZMQ

released
{
    "@context": "/terms/",
    "@id": "/measurement-sets/IGVFDS3910MZMQ/",
    "@type": [
        "MeasurementSet",
        "FileSet",
        "Item"
    ],
    "accession": "IGVFDS3910MZMQ",
    "aliases": [
        "igvf:multiome_scatac_seq"
    ],
    "assay_term": {
        "@id": "/assay-terms/OBI_0002764/",
        "term_name": "single-cell ATAC-seq"
    },
    "audit": {
        "ERROR": [
            {
                "category": "inconsistent document type",
                "detail": "Sequence file [IGVFFI2658WGRW](/sequence-files/IGVFFI2658WGRW/) has `file_format_specification` [d8ce793f-933b-45ea-9611-1c3f80cb7e11](/documents/d8ce793f-933b-45ea-9611-1c3f80cb7e11/) with `document_type` plasmid map. File format specifications are excepted to be documents have type file format specification.",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_file_format_specifications",
                "path": "/sequence-files/IGVFFI2658WGRW/"
            },
            {
                "category": "upload status not validated",
                "detail": "Sequence file [IGVFFI2658WGRW](/sequence-files/IGVFFI2658WGRW/) has `upload_status` pending. Files are expected to be validated.",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_upload_status",
                "path": "/sequence-files/IGVFFI2658WGRW/"
            },
            {
                "category": "missing related files",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has seqspec configuration file [IGVFFI1190FVNM](/configuration-files/IGVFFI1190FVNM/) which links to sequence file(s): [IGVFFI4710CQYT](/sequence-files/IGVFFI4710CQYT/) which do not link to this file set. All files associated with a seqspec (both sequencing and seqspec files) are expected to be linked to the same file set.",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_files_associated_with_incorrect_fileset",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "unexpected multiome size",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has `multiome_size`. Only measurement sets from multiome assays are expected to specify a multiome size.",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_related_multiome_datasets",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "upload status not validated",
                "detail": "Configuration file [IGVFFI1190FVNM](/configuration-files/IGVFFI1190FVNM/) has `upload_status` pending. Files are expected to be validated.",
                "level": 60,
                "level_name": "ERROR",
                "name": "audit_upload_status",
                "path": "/configuration-files/IGVFFI1190FVNM/"
            }
        ],
        "INTERNAL_ACTION": [
            {
                "category": "mismatched status",
                "detail": "Released measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has in progress subobject in vitro system [IGVFSM2795QSOV](/in-vitro-systems/IGVFSM2795QSOV/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "mismatched status",
                "detail": "Released human donor [IGVFDO9208RPQQ](/human-donors/IGVFDO9208RPQQ/) has in progress subobject publication [59c63dd9-b5fb-4768-8045-ed8c0003a40c](/publications/59c63dd9-b5fb-4768-8045-ed8c0003a40c/).",
                "level": 30,
                "level_name": "INTERNAL_ACTION",
                "name": "audit_item_status",
                "path": "/human-donors/IGVFDO9208RPQQ/"
            }
        ],
        "NOT_COMPLIANT": [
            {
                "category": "missing sequencing kit",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has sequence file(s) [IGVFFI2658WGRW](/sequence-files/IGVFFI2658WGRW/), [IGVFFI9343YZPC](/sequence-files/IGVFFI9343YZPC/) which lack specification of a `sequencing_kit`. Sequence files should specify a sequencing kit.",
                "level": 50,
                "level_name": "NOT_COMPLIANT",
                "name": "audit_inconsistent_sequencing_kit",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "missing sequence specification",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has sequence file(s): [IGVFFI2658WGRW](/sequence-files/IGVFFI2658WGRW/) which do not have any `seqspecs`. Sequence files in a file set are expected to link to a sequence specification file.",
                "level": 50,
                "level_name": "NOT_COMPLIANT",
                "name": "audit_missing_seqspec",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "missing NIH certification",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has a sample [IGVFSM2795QSOV](/in-vitro-systems/IGVFSM2795QSOV/) that lacks any `institutional_certificates` issued to the lab that submitted this file set. Measurement sets for mapping assays or controlled access characterization assays involving samples with a human origin are expected to link to the relevant institutional certificates issued to a matching lab and award.",
                "level": 50,
                "level_name": "NOT_COMPLIANT",
                "name": "audit_missing_institutional_certification",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "missing protocol",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has no `protocols`. Measurement sets are expected to specify the experimental protocol utilized for conducting the assay on protocols.io.",
                "level": 50,
                "level_name": "NOT_COMPLIANT",
                "name": "audit_unspecified_protocol",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            }
        ],
        "WARNING": [
            {
                "category": "missing analysis",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) is a raw data set with files, but is not listed in any `input_file_sets` for any analysis sets. Raw data sets with files are expected to be associated with at least one analysis set.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_input_for",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            },
            {
                "category": "inconsistent preferred assay title",
                "detail": "Measurement set [IGVFDS3910MZMQ](/measurement-sets/IGVFDS3910MZMQ/) has `assay_term` single-cell ATAC-seq, but `preferred_assay_title` VAMP-seq. Measurement sets are expected to specify an appropriate preferred assay title for its respective assay term.",
                "level": 40,
                "level_name": "WARNING",
                "name": "audit_preferred_assay_title",
                "path": "/measurement-sets/IGVFDS3910MZMQ/"
            }
        ]
    },
    "award": {
        "@id": "/awards/HG012051/",
        "component": "networks",
        "contact_pi": {
            "@id": "/users/7138e67a-2af5-4a48-90bc-04ea95b53c78/",
            "title": "Danwei Huangfu"
        },
        "title": "Genomic control of gene regulatory networks governing early human lineage decisions"
    },
    "control_for": [
        {
            "@id": "/measurement-sets/IGVFDS5330YIDV/",
            "accession": "IGVFDS5330YIDV",
            "aliases": [
                "igvf:basic_measurement_set"
            ]
        }
    ],
    "creation_timestamp": "2023-04-27T18:51:25.198759+00:00",
    "donors": [
        {
            "@id": "/human-donors/IGVFDO9208RPQQ/",
            "accession": "IGVFDO9208RPQQ",
            "aliases": [
                "igvf:donor_of_K562"
            ],
            "sex": "female",
            "status": "released",
            "taxa": "Homo sapiens"
        }
    ],
    "externally_hosted": false,
    "file_set_type": "experimental data",
    "files": [
        {
            "@id": "/sequence-files/IGVFFI2658WGRW/",
            "accession": "IGVFFI2658WGRW",
            "aliases": [
                "igvf:example_fastq_01",
                "jay-shendure:example_fastq_01_alt_alias"
            ],
            "content_type": "reads",
            "controlled_access": false,
            "creation_timestamp": "2023-05-23T20:29:58.899328+00:00",
            "file_format": "fastq",
            "file_size": 9898933494,
            "href": "/sequence-files/IGVFFI2658WGRW/@@download/IGVFFI2658WGRW.fastq.gz",
            "s3_uri": "s3://igvf-files-dev/2023/05/23/21cc5af6-5c36-4913-af85-440b4b61f383/IGVFFI2658WGRW.fastq.gz",
            "sequencing_platform": {
                "@id": "/platform-terms/EFO_0004203/",
                "term_name": "Illumina HiSeq 2000"
            },
            "submitted_file_name": "/path/to/sequence_file.fastq.gz",
            "upload_status": "pending"
        },
        {
            "@id": "/configuration-files/IGVFFI1190FVNM/",
            "accession": "IGVFFI1190FVNM",
            "aliases": [
                "igvf:example_configuration_file_01"
            ],
            "content_type": "seqspec",
            "creation_timestamp": "2023-09-19T20:11:56.580713+00:00",
            "file_format": "yaml",
            "file_size": 1240000,
            "href": "/configuration-files/IGVFFI1190FVNM/@@download/IGVFFI1190FVNM.yaml.gz",
            "s3_uri": "s3://igvf-files-dev/2023/09/19/718d7475-e11b-4a1f-bdfa-899abf6c711f/IGVFFI1190FVNM.yaml",
            "submitted_file_name": "/path/to/seqspec.yaml",
            "upload_status": "pending"
        },
        {
            "@id": "/sequence-files/IGVFFI9343YZPC/",
            "accession": "IGVFFI9343YZPC",
            "content_type": "PacBio subreads",
            "controlled_access": false,
            "creation_timestamp": "2023-05-08T17:16:55.623037+00:00",
            "file_format": "bam",
            "file_size": 235234435,
            "href": "/sequence-files/IGVFFI9343YZPC/@@download/IGVFFI9343YZPC.bam",
            "s3_uri": "s3://igvf-files-dev/2023/05/08/29b7f066-9d13-4663-8fe2-cd6847ec9c5c/IGVFFI9343YZPC.bam",
            "sequencing_platform": {
                "@id": "/platform-terms/EFO_0004203/",
                "term_name": "Illumina HiSeq 2000"
            },
            "upload_status": "validated"
        }
    ],
    "input_for": [],
    "lab": {
        "@id": "/labs/danwei-huangfu/",
        "title": "Danwei Huangfu, MSKCC"
    },
    "multiome_size": 2,
    "preferred_assay_title": "VAMP-seq",
    "related_multiome_datasets": [
        {
            "@id": "/measurement-sets/IGVFDS2075SWXE/",
            "accession": "IGVFDS2075SWXE"
        }
    ],
    "release_timestamp": "2023-04-27T18:51:25.181642+00:00",
    "samples": [
        {
            "@id": "/in-vitro-systems/IGVFSM2795QSOV/",
            "@type": [
                "InVitroSystem",
                "Biosample",
                "Sample",
                "Item"
            ],
            "accession": "IGVFSM2795QSOV",
            "classifications": [
                "cell line"
            ],
            "construct_library_sets": [
                {
                    "@id": "/construct-library-sets/IGVFDS0948BMCL/",
                    "accession": "IGVFDS0948BMCL",
                    "file_set_type": "guide library",
                    "summary": "Guide (sgRNA) library targeting TF binding sites, phenotype-associated variants genome-wide associated with DiGeorge syndrome"
                }
            ],
            "sample_terms": [
                {
                    "@id": "/sample-terms/EFO_0002067/",
                    "@type": [
                        "SampleTerm",
                        "OntologyTerm",
                        "Item"
                    ],
                    "aliases": [
                        "igvf:K562"
                    ],
                    "status": "released",
                    "summary": "K562",
                    "term_name": "K562"
                }
            ],
            "status": "in progress",
            "summary": "K562 cell line, female, Homo sapiens transfected with a guide library",
            "taxa": "Homo sapiens"
        }
    ],
    "schema_version": "23",
    "status": "released",
    "submitted_by": {
        "@id": "/users/1e75d989-a438-4d77-a451-8a297fd3636e/",
        "title": "Ian Whaling"
    },
    "submitted_files_timestamp": "2023-05-08T17:16:55.623037+00:00",
    "summary": "VAMP-seq integrating a guide (sgRNA) library targeting TF binding sites, phenotype-associated variants genome-wide associated with DiGeorge syndrome",
    "uuid": "5663d0c7-faee-4c10-8ef5-c827fd74ad28"
}