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5 items
  • MeasurementSet
    IGVFDS1953KIOT
    CRISPR prime editing VAMP-seq integrating a guide (sgRNA) library targeting sequence variants in a genomic locus
    Doug Fowler, UW
    Sample Summary
    Homo sapiens (male) THP-1 cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library
    released
  • MeasurementSet
    IGVFDS5518TESD
    CRISPR prime editing Variant-EFFECTS integrating a guide (sgRNA) library targeting sequence variants in a genomic locus
    Jesse Engreitz, Stanford
    Sample Summary
    Homo sapiens (male) Jurkat cell line modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library
    released
  • MeasurementSet
    IGVFDS3910MZMQ
    CRISPR VAMP-seq integrating a guide (sgRNA) library targeting TF binding sites, phenotype-associated variants genome-wide associated with DiGeorge syndrome
    Danwei Huangfu, MSKCC
    Sample Summary
    Homo sapiens (female) K562 cell line transfected with a guide library
    released
  • MeasurementSet
    IGVFDS2075SWXE
    CRISPR scRNA-seq integrating a guide (sgRNA) library targeting TF binding sites, phenotype-associated variants genome-wide associated with DiGeorge syndrome
    Danwei Huangfu, MSKCC
    Sample Summary
    multiplexed sample: Homo sapiens (female) H9 differentiated cell specimen induced to neural progenitor cell for 30 minutes (cellular sub pool: K80_A2); Homo sapiens (male) endothelial cell line (sorting details: detail of the fraction) depleted of lipopolysaccharide for 6 hours, transfected with a guide library; ... and 4 more samples
    released
  • MeasurementSet
    IGVFDS1317BKCD
    SHARE-seq (SHARE-seq)
    Lior Pachter, Caltech
    Sample Summary
    Mus musculus B6XCast (male, 15-25 months) adrenal gland tissue (cellular sub pool: AT9029) associated with pulmonary arterial hypertension, treated with 10 mM leucine for 6 hours
    released