IGVF

/

MeasurementSet

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Assay

SHARE-seq
1
in vitro CRISPR screen assay
1
in vitro CRISPR screen using flow cytometry
1
single-cell ATAC-seq
1
single-cell RNA sequencing assay
1

Preferred Assay Title

VAMP-seq
2
10x multiome
1
SHARE-seq
1
Variant-EFFECTS
1

Construct Library Data

guide library
3
expression vector library
1

Investigated Gene

INTS11
1

Sequencing Platform

Illumina HiSeq 2000
1

5 items

MeasurementSet
IGVFDS1953KIOT
VAMP-seq integrating a expression vector library of tile tile3 of INTS11 (AA 299-461) (sequence variants)
Doug Fowler, UW
Sample Summary
HEK293T cell line, female, Homo sapiens transfected with a expression vector library (MOI of 1)
released
MeasurementSet
IGVFDS5518TESD
prime editing Variant-EFFECTS integrating a guide (sgRNA) library targeting sequence variants in a genomic locus
Jesse Engreitz, Stanford
Sample Summary
Jurkat cell line, male, Homo sapiens modified with CRISPR prime editing Sp-nCas9-M-MLV RT (PE2), transfected with a guide library
released
MeasurementSet
IGVFDS3910MZMQ
VAMP-seq integrating a guide (sgRNA) library targeting TF binding sites, phenotype-associated variants genome-wide associated with DiGeorge syndrome
Danwei Huangfu, MSKCC
Sample Summary
K562 cell line, female, Homo sapiens transfected with a guide library
released
MeasurementSet
IGVFDS2075SWXE
single-cell RNA sequencing assay (10x multiome) integrating a guide (sgRNA) library targeting TF binding sites, phenotype-associated variants genome-wide associated with DiGeorge syndrome
Danwei Huangfu, MSKCC
Sample Summary
K562 cell line, female, Homo sapiens transfected with a guide library
released
MeasurementSet
IGVFDS1317BKCD
SHARE-seq (SHARE-seq)
Lior Pachter, Caltech
Sample Summary
adrenal gland tissue (cellular sub pool: AT9029), male, Mus musculus B6XCast (15-25 months) associated with pulmonary arterial hypertension, treated with 10 mM leucine for 6 hours
released