networks

HG012047

IGVF

current

Defining causal roles of genomic variants on gene regulatory networks with spatiotemporally-resolved single-cell multiomics

ff554121-5ddd-4c0a-93fb-0809f389d170

predictive modeling

HG012022

IGVF

current

Supporting IGVF by modeling genetics, function, and phenotype with machine learning

f81dd63f-dc65-4e46-96b8-2d44f9456181

predictive modeling

HG012009

IGVF

current

Predicting the impact of genetic variants, genes and pathways on human disease

e367d3d4-bf15-4821-99d6-055e52910bc9

networks

HG012103

IGVF

current

Deciphering the Genomics of Gene Network Regulation of T Cell and Fibroblast States in Autoimmune Inflammation

df3cd6b4-dba8-40c7-8f44-3c8f94e2fe24

functional characterization

HG012053

IGVF

current

High-Throughput Functional Annotation of Gene Regulatory Elements and Variants Critical to Complex Cellular Phenotypes

cfdf836c-b9b5-4714-aa92-058214998cfc

data coordination

HG012012

IGVF

current

A Data and Administrative Coordinating Center for the Impact of Genomic Variation on Function Consortium

c933e5d0-f381-462b-bf42-e640e77f46fd

mapping

HG012076

IGVF

current

Single-cell Mapping Center for Human Regulatory Elements and Gene Activity

c62af563-4954-4172-984b-11883485119b

functional characterization

HG011972

IGVF

current

Stanford Center for Connecting DNA Variants to Function and Phenotype

c0c27048-195d-4754-98c5-b513a1a4d2c0

mapping

HG011986

IGVF

current

A foundational resource of functional elements, TF footprints and gene regulatory interactions

b4493512-d006-4cd2-b004-385979a91eac

functional characterization

HG011996

IGVF

current

Multiscale functional characterization of genomic variation in human developmental disorders

a7485ebf-8238-4d36-8e1d-203fefd85595

predictive modeling

HG012069

IGVF

current

Predicting context-specific molecular and phenotypic effects of genetic variation through the lens of the cis-regulatory code

9ff6df18-d3fd-4aa0-89e9-53a1449ee240

functional characterization

HG011966

IGVF

current

Massively parallel characterization of variants and elements impacting transcriptional regulation in dynamic cellular systems

85522f5c-3617-4a2c-9f01-c8740b60f401

data coordination

HG012070

IGVF

current

WashU-Northwestern Genomic Variation and Function Data and Administrative Coordinating Center

5f62347b-fa5c-4b05-b146-b5da565b9f83

predictive modeling

HG012064

IGVF

current

Predictive Modeling of the Functional and Phenotypic Impacts of Genetic Variants

52fd80a2-07fa-4aba-b06b-dc13e6bee3e5

functional characterization

HG012010

IGVF

current

Comprehensive characterization of variants underlying heart and blood diseases with CRISPR base editing

44651e8f-e2f2-4b51-b1a4-334d4d1c93c0

networks

HG012041

IGVF

current

Linking genome variation to transcriptional network dynamics in human B cells

41335c62-9e4b-4ae1-8fe9-17f4b5324f78

networks

HG012079

IGVF

current

Leveraging genetic variation to dissect gene regulatory networks of reprogramming to pluripotency

2f2c3b3d-5cea-4525-adb3-025bebb127df

mapping

HG012077

IGVF

current

Center for Mouse Genomic Variation at Single Cell Resolution

289740c5-e032-490d-9aac-88a7fdb6a589

networks

HG012059

IGVF

current

The impact of genomic variation on environment-induced changes in pancreatic beta-cell states

2234214f-36a7-4b95-b9b4-9c799933e5ac

functional characterization

HG012003

IGVF

current

Systematic in vivo characterization of disease-associated regulatory variants

1c2078f3-8e35-4ed5-9f12-3356ec3b7420

functional characterization

HG011989

IGVF

current

Molecular phenotyping of ~100,000 coding variants across Mendelian disease genes

1a6090bb-a7dc-497a-b0d0-f6c9b9c634ab

networks

HG012051

IGVF

current

Genomic control of gene regulatory networks governing early human lineage decisions

17d8d414-8a80-4fc0-879e-219eedc9cd7d

functional characterization

HG011969

IGVF

current

The Center for Actionable Variant Analysis; measuring variant function at scale

14e237c9-f0e1-4296-ab13-472de0588e2e

predictive modeling

HG011967

IGVF

current

Design, prediction, and prioritization of systematic perturbations of the human genome

1098f89c-a008-47a8-a8da-39e983ab6d37

predictive modeling

HG012039

IGVF

current

Linking Variants to Multi-scale Phenotypes via a Synthesis of Subnetwork Inference and Deep Learning

0233624d-b75e-4481-9f96-87d44a762509